2011 Life Sciences Chairmen's Distinguished Award
Melissa Knothe Tate
Professor of Biomedical Engineering
Case Western Reserve University
Cleveland, Ohio
Dr. Melissa Knothe Tate is an internationally recognized leader in the fields of orthopaedic mechanobiology as well
as the development and clinical translation of novel technologies and materials.
Dr. Knothe Tate joined the nascent field of orthopaedic mechanobiology two decades ago, as a student at Stanford
University, where she earned dual BS degrees in Biological Sciences and Mechanical Engineering in 1988. Thereafter,
she transferred her research and academic pursuits to the Swiss Federal Institute of Technology in Zurich, Switzerland,
where she earned a Dipl. Masch. Ing., 1994 in Mechanical Engineering and a Ph.D. degree (Dr. sc. techn.ETH, 1998) in
Mechanical and Biomedical Engineering. In 1998, she was awarded the Georg Fischer Prize for the most outstanding
dissertation at the ETH Zurich.
For several years, Dr. Knothe Tate headed the Bone Mechanobiology Research Group at the AO Research Institute in Davos,
as well as the Computational Mechanobiology Research Group at the Institute of Biomedical Engineering in Zurich.
She spent the year 2000 as Visiting Professor at the Mt. Sinai School of Medicine Department of Orthopaedics.
In January 2001, she joined the Departments of Biomedical Engineering and Orthopaedic Surgery at the Cleveland Clinic,
where she received several awards for innovation in the R&D sector.
In July 2004, she joined the faculty of Case Western Reserve University, where she was the first Joint Professor
of Mechanical & Aerospace and Biomedical Engineering. In addition to being recently elected to the College of
Fellows of the American Institute for Medical and Biological Engineering (2011), Dr. Knothe Tate has received
prestigious awards from the Society for Mathematics and Biology and the Wallace H. Coulter Foundation.
Through the National Science Foundation, Dr. Knothe Tate recently led a new national research initiative in the area
of stem cell mechanics during prenatal development, and postnatal growth and healing. Recently, her research has expanded
to the areas of cellular and biofluid mechanics as well as development and clinical translation of novel bio-inspired flow
directing materials and implants.
She is currently on sabbatical, carrying out translational research in Europe on a Humboldt Foundation Fellowship for
Senior Researchers.
The Christopher Columbus Fellowship Foundation is honored to have had the assistance of the following distinguished individuals serving on the 2011
Life Sciences Awards Evaluation Committee:
- Russell A. Bantham, Esquire
McLean, VA
- Alan Bronstein
Chemistry Teacher
Central High School
Philadelphia, PA
- Christine Leyden
Senior Vice President and Chief Accreditation Officer
URAC
Washington, D.C.